After his spy school training, Ben Ripley is on his first solo mission of infiltrating the White House and stopping a possible presidential assassination, but when his assignment runs into trouble, he isn't sure he can trust his friends for help.

With SPYDER apparently defeated, thirteen-year-old Benjamin Ripley is hoping for some peace at spy school, but when the CIA conference room next to where Ben and Alexander are trying to explain everything to Ben's parents (no easy task) is blown up, suspicion falls on fellow trainee (and secret crush) Erica.

Twelve-year-old Ben's unexpected success outside the classroom causes the CIA to activate him for a mission to become friends with Jessica Shang, daughter of a suspected Chinese crime boss.